Glucosamine Sulfate - 1300 MG - Glucosamine sulfate comes from shellfish and is proven to ease joint pain, as it can slow or even prevent the collagen that cartilage is made of from breaking down. This also makes it a very effective treatment for osteoarthritis (1).
Unfortunately, the way in which it is used is incorrect. While the 1,300 mg present falls in the optimal range of 500 to 1,500 mg, it is all delivered in a single dose, rather than 2 to 3 smaller doses as recommended to maximise the benefits of glucosamine.
This means it is likely that it won't do its job as effectively as it otherwise could.
MSM (Methylsulfonylmethane) - 400 MG - MSM is a chemical most commonly found in green vegetables, fruits, and plants that is high in sulphur and known for its anti inflammatory and antioxidant properties. It can aid joint health, treat osteoarthritis, and prevent inflammation and oxidative stress and damage (2).
The problem is, for it to do these things, you must consume 3,000 mg of MSM per day. As the 400 mg present in each serving of Jointlax is just a fraction of this, it is highly unlikely it will benefit your joints.
White Willow Bark Extract - 250 MG - White Willow bark extract contains salicin, which is similar to what is used to make aspirin. It is sometimes added to joint supplements, as there are claims that it can ease muscle and joint pain, and treat arthritis symptoms, fevers, flus, and some other illnesses.
The issue is, all of these claims are just that, claims, as there is no scientific evidence to back them up (3). You therefore simply can't count on its inclusion to add any benefits to the Jointlax formula.
Boswellia Serrata Gum Extract - 75 MG - Boswellia serrata gum extract is a resin from the frankincense tree which contains boswellic acid. It is often put in joint support dietary supplements, as there are claims that it can ease acute pain and inflammation in the joints, swelling in the brain, and osteoarthritis symptoms (4).
This is a reasonable inclusion, but in the extract form used by jointlax as it isn't a high concentration version the supporting studies say at least 1,200 mg must be consumed each day for it to be effective. This means the 75 mg present in each serving of Jointlax is virtually guaranteed to be useless. Other supplements manage to get enough boswellic acid from 100mg, making this even worse for our Jointlax review.
Tulsi (Holy Basil Extract) - 50 MG - Tulsi is best known for its purported ability to improve libido, fertility, and testosterone levels, but there are also claims that it is an antioxidant and adaptogen that can protect both the liver and body from oxidative damage (5).
Unfortunately, as none of these claims have yet been proven and even supporters say that you need to take 500 mg of tulsi each day, the 50 mg present in Jointlax will almost certainly do nothing.
Turmeric Root Extract - 50 MG -Turmeric root extract
contains the potent antioxidant and anti-inflammatory curcumin and is made from the curcuma longa plant.
It can reduce inflammation, cholesterol, blood sugar, and blood pressure levels, restore joint function, ease joint pain, treat anxiety, depression, and osteoarthritis, make other antioxidant chemicals in your body more effective, protect the liver, and help with weight management.
The problem is, 500 mg of curcumin must be consumed each day for it to produce these benefits (6). And Curcumin makes up less than 20% of turmeric. As Jointlax has just a fraction of this at 50 mg of turmeric root extract per serving, it will have no effect at all.
CMO (Cetyl Myristoleate) - 50 MG - CMO is made from monounsaturated fatty acids and alcohol. It lubricates joints, reduces inflammation, and even helps treat fibromyalgia, arthritis, and other musculoskeletal conditions (7).
Yet again though, the 250 mg daily dose required to be effective is far below the 50 mg present in Jointlax, so it can't do what it is supposed to here.
Ginger Root Extract - 25 MG - Ginger root extract is a potent antioxidant and inti-inflammatory that can prevent oxidative damage, support joint health, reduce cholesterol levels, boost the immune system, enhance digestion, and even elevate the absorption and efficacy of the supplement's other ingredients (8).
With doses of around 1,000 mg required each day for it to be effective though, the 25 mg in each serving of Jointlax is virtually worthless. There are some extract varients of ginger that can work from as low as 250mg, but these are expensive and even that is 10x more than in Jointlax.
Mythocondro (Vegan Chondroitin Sulfate) - 20 MG - Chondroitin is one of the main components of cartilage and a common dietary supplement ingredient, as it can ease joint pain and stiffness, and relieve the symptoms of osteoarthritis (9).
However, not only is 1,200 mg of chondroitin usually required each day, but it is usually made from animal products. This means the vegan chondroitin sulfate used in Jointlax isn't strong enough to be of use, and may not work even if it did, as it has been far less studied.
Bromelain (From Pineapple) - 20 MG - Bromelain is an enzyme found in pineapples which can improve digestion, protein metabolism, and immunity, ease heartburn and nasal congestion, and reduce inflammation and joint pain. The issue is, you need to consume 200 to 2,000 mg per day to produce these effects (10).
The mere 20 mg in every serving of Jointlax will therefore do virtually nothing.
L-Glutamic Acid - 20 MG - L-glutamic acid is an amino acid that is involved in the health and function of nerve and brain cells. It is said to enhance both your memory and ability to learn, while there is also some evidence that it can help to provide muscle and joint pain relief as well (11).
Unfortunately, only its brain health benefits have ever been proven, meaning it likely won't produce the desired effects in a joint support supplement like Jointlax.
Black Catechu Bark - 10 MG - The bark from the black catechu tree is said to have antibacterial, antifungal, antioxidant, anti inflammatory, and anti diarrheal properties, and it has long been used in ayurvedic medicine to ease joint swelling or painful joints and protect the blood and the liver.
While current studies show that it may have some antioxidant properties, there is very proof that it can do what is claimed (12). This means it can't be relied upon to produce results in a natural supplement like Jointlax.
L-Cysteine (L-Cysteine Hydrochloride) - 9.8 MG - L-cysteine is a semi-essential amino acid that plays a role in the production protein, especially the protein found in the hair, nails, and skin, as well as the antioxidant glutathione and a range of minerals (13).
Studies suggest it may provide some level of joint support, but without any hard evidence it simply can't be relied upon to produce results in Jointlax.
Hyaluronic Acid - 4 MG - Hyaluronic acid is a type of polysaccharide known to boost skin elasticity and healing time, reduce wrinkles and the signs of aging, and improve the health of the cartilage, eyes, and joints (14).
Unfortunately, studies suggest 200 mg a day are needed to produce these effects. As Jointlax has just 20 mg per serving, it is far too weak to be of any use.
Rutin Powder - 2 MG - Rutin is a flavonoid found in a number of plant based foods that some people say is an antioxidant and anti inflammatory, which is capable of supporting healthy cellular regeneration, combating diseases, and improving brain functions (15).
None of these benefits are anything more than speculation at this point though, and it is likely it adds nothing to the Jointlax formula.
Bioperine Black Pepper Extract - 5 MG - Bioperine is often put in joint supplements not for its effect on the joints, but because it can boost the bioavailability, absorption, and efficacy of the other ingredients, some of which won't work without it.
However, as 10 - 20 mg of black pepper extract is required to produce these effects, the 5 mg in each serving of Jointlax is unlikely to do anything (16).
References
1 - https://www.nccih.nih.gov/health/glucosamine-and-chondroitin-for-osteoarthritis
2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
3 - https://pubmed.ncbi.nlm.nih.gov/25997859/
4 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309643/
5 - https://examine.com/supplements/holy-basil/
6 -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/
7 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340442/
8 - https://www.ncbi.nlm.nih.gov/books/NBK565886/
9 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035477/
10 -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/
11 - https://pubchem.ncbi.nlm.nih.gov/compound/33032
12 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680622/
13 - https://pubchem.ncbi.nlm.nih.gov/compound/Cysteine
14 - https://www.ncbi.nlm.nih.gov/books/NBK482440/
15 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355559/
16 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634921/